There are many drugs on the market containing PDE-5 inhibitors in their composition, which is why we can freely adjust them to your needs and preferences. Their prices are also different, so before you decide to use them, you should answer the question – how much you can spend on their purchase. However, not always more expensive drugs are the better and more effective, which is also important when selecting and analyzing the composition. They often have the same composition and action, while the difference in price can be up to 50%. Always look, however, for the PDE-5 inhibitors, including sildenafil, which you will find in the medicines Viagra and Kamagra.
An important factor determining the choice is also the duration of action. Sildenafil shows its activity in the male body for 4-6 hours, however, it can happen longer, up to 10 hours. Shorter action is also possible, which is influenced by many factors – diet, physical activity, stimulants and concomitant diseases. You can also choose from various forms of medicines. At your disposal are tablets that we drink with water, liquid gels, effervescent tablets and lozenges. They contain the same active substance in the same amount.
A visit to a doctor is necessary not only to receive a prescription for a medicine, but also to apply it with all safety rules. It is not possible in every case to take PDE-5 inhibitors, which results from the patient’s state of health. Are these drugs that do not threaten your health and life? Learn the most important contraindications to their use.
- Taking concomitant nitric oxide donors simultaneously.
- Use of the drug in the event of an increased risk of cardiovascular disease, heart failure and angina pectoris.
- With hepatic failure.
- At blood pressure equal to or below 90/50 mmHg.
- After a heart attack.
- In the case of diagnosed inherited tendency to conduct degeneration of the retina.
When taking medicines containing sildenafil, other components from the group of phosphodiesterase-5 inhibitors, and other medicines used to treat erectile dysfunction.
There are also factors in which caution should be exercised when using drugs for potency. Belong to them:
- Anatomical member deformation: fibrosis of penile corpora of the penis, visible folds and Peyronie’s disease;
- Diseases causing the emergence of priapism. It is a painful and long-lasting erection of the penis, which occurs even without sexual stimulation;
- Peptic ulcer disease;
- Alpha-blockers contributing to the occurrence of orthostatic hypotension in combination with the active substance contained in the medicin;
- Irregularities in blood coagulation.
What are possible side effects?
Potency medications should be taken as directed by the doctor and as recommended by the manufacturer. There is a risk, albeit slight, of adverse reactions. Most often they appear with the wrong use of the drug. Acute symptoms include: headache and muscle aches, dizziness, nausea, hot flushes and visual disturbances. We will meet less often with increased pressure, nose and penis bleeding, eye congestion, dry mouth, vomiting, hypersensitivity to light and pain in the limbs. There are also side effects occurring least frequently. It is the pressure of the throat, the swelling of the eyelids, the split personality, stroke, heart attack, worsening of hearing and fainting.
Doses of sildenafil
Both Viagra and Kamagra are present in 3 doses, which are used depending on the stage of the problem and possible contraindications to taking a larger dose.
25 mg – the lowest available dose, recommended for young men with smaller erectile dysfunction, as well as for men with a finer body build. A very good option to start with. The risk of side effects is the smallest, but at the same time it is characterized by high effectiveness at the level of over 60%.
50 mg – the dose is usually chosen, it can be increased or decreased depending on the man’s reaction. Clinical studies show that positive results in the treatment of impotence in men with sildenafil 50 mg were obtained in 74% of men.
100 mg – the largest dose used in special cases, most often when smaller do not bring the desired results. It shows very high efficiency, at the level of 83%.
Sildenafil and clinical trials
Sildenafil is one of those substances whose efficacy is confirmed by clinical trials. This causes that he enjoys great trust among men, and its use is a safe method of fighting impotence.
In the meta-analysis Fri Sildenafil (Viagra) for male erectile dysfunction: a meta-analysis of clinical trial research results that present the satisfaction of patients using sildenafil at specific doses. The test lasted for 4 weeks and was carried out among men who took the drug at home, only when they felt the need.This results: 25 mg – 193 for 312 men, or 62% confirmed its effectiveness 50 mg – 378 for 511 men, i.e. 74% confirmed its effectiveness 100 mg – 415 per 506 men, i.e. 82% confirmed its effectiveness 200 mg – 152 per 191 men, i.e. 80% confirmed its effectiveness. The greatest effectiveness was demonstrated by the 100 mg dose, i.e. the largest one available on the market in one tablet . 200 mg is a dose used in very few cases when the problem is extremely high. Viagra and its substitutesViagra was the first drug for potency, which brought her so much fame, especially that it shows excellent performance, which is confirmed by the results of the tests carried out on sildenafil . It is also the drug most often chosen by men struggling with erection problems. Its price is higher due to its reputation, company tradition and a long history. It can be said that Viagra was the model for other drugs that appeared on the market later. Currently, we can choose from many other alternatives with the same composition and mechanism of action. One of them is Kamagra, which is produced by the Indian pharmaceutical company Ajanta Pharma, which makes it a product characterized by a lower price than substitutes produced by European companies. Kamagra contains sildenafil, an ingredient that improves blood supply to the penis, which translates into the ability to achieve an erection, as well as its elongation. What distinguishes him is the few forms in which he appears. You can opt for tablets, fruit gels, effervescent tablets and sucking. In each of these cases you will find options of 25 mg, 50 mg and 100 mg, so regardless of your taste preferences, you can choose the perfect option for yourself. It is a drug intended for men after 18 years of age, in other words, as in the case of Viagra. The best dose is recommended for men over 40 years of age, as well as for those with impotence at an advanced stage. The smaller ones will be perfect for starters, there is always the possibility to increase. You can buy potency online Viagra and Kamagra at your local pharmacy. Many men in such situations, however, are accompanied by embarrassment and shame, sometimes even giving up on the purchase. An alternative is to buy a drug for potency via the Internet. In this case, a prescription is also required, these are prescription-only medicines. We are aware of the importance of discretion and a sense of security for you, which is why we ensure that all personal data of our clients are protected. What’s more, the ordered products are packed in universal packaging, so that they do not indicate their content, which will certainly allow you to pick up your parcel without restraint.